The DEFINE PCI study used iFR pullback to understand the rate and causes of residual ischemia in 500 patients undergoing contemporary PCI. Early results find that residual ischemia is common, and causes are treatable.1
1 in 4 patients with angiographically successful PCI left the cath lab with residual ischemia.1
Of the patients with residual ischemia, 81.6% were caused by an untreated, angiographically inapparent physiologically focal stenosis of varying location.1
If all focal lesions had been successfully treated, only 4.9% of patients would remain with residual ischemia, a reduction of 79%.1
Physiologic miss took place in varying locations.1
The findings from DEFINE PCI help support the value of using advanced physiologic guidance only offered by Philips to help decide not just whether to treat, but where to treat.
Without knowing the distribution of ischemia within the vessel, important segments can be missed and left untreated.
iFR Co-registration, from Philips, helps you:
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In this program, Professor Sharp and Dr. Gallagher will present a case of an IVUS-guided PCI of bifurcation lesion. They will discuss and demonstrate the various strategies available for this LAD/Diag bifurcation lesion and how IVUS plays ...
Listen to important clinical implications of how iFR pullbacks are changing how success in PCI is assessed in the DEFINE PCI study results discussion.
1. Jeremias A et al. The DEFINE PCI Trial: Blinded Physiological Assessment of Residual Ischemia after Successful Angiographic Percutaneous Coronary Intervention, presented at ACC 2019.